Obinna Adumanya
Imo State Polytechnic, Nigeria
Title: PHOTOPROTECTIVE POTENTIALS OF Hibiscus sabdariffa “ZOBO†EXTRACT FROM UV LIGHT USING ALBINO MICE MODEL.
Biography
Biography: Obinna Adumanya
Abstract
The photoprotective potentials of methanolic extract of Hibiscus sabdariffa “zobo” leaves from UV light was studied using albino mice. A total of ten albino mice weighing between 26 g – 31 g were grouped into five of two mice each. Group A received distilled water ad libitum and were protected from UV light, group B received water ad libitum and were exposed to UV light, group C were orally given 0.1mg/kg body weight of the extract and exposed to UV light, group D received 0.1mg/kg body weight orally and complete topical body application of the extract, while group E received complete topical body application of the extract only. The treatments lasted for five days. Erythema and haemoglobin levels were used as indices to assess the photoprotective potentials of the methanolic Hibiscus sabdariffa leaves extract. Progressive degrees of erythema were observed on all the groups exposed to UV light compared to the one protected from UV light. While Hb levels were also affected significantly compared to the groups protected from UV light and topical application of the extract. The study suggests that methanolic extract of Hibiscus sabdariffa leaves might be of protective importance from UV lights, especially topical application.